Amycaine

Amycaine Suspension is a scientifically formulated gastro-protective and antacid suspension from Amista Labs, designed to provide fast and effective relief from acidity, heartburn, acid reflux, gastritis, and ulcer-related pain. It combines the acid-neutralizing properties of aluminium and magnesium hydroxides with the local anesthetic action of Oxetacaine, making it especially beneficial for patients suffering from painful gastric conditions.

The Potent Composition

Amycaine Suspension is a triple-action formula. Each 5ml of the suspension contains a precise blend of three active pharmaceutical ingredients (APIs) that work synergistically to restore gastric comfort:

1. Oxetacaine BP (10 mg): Unlike standard antacids that only neutralize acid, Amycaine includes Oxetacaine, a potent local anesthetic. Oxetacaine is unique because it remains effective even in highly acidic environments (low pH) found in the stomach. It works by numbing the nerve endings in the stomach lining, providing immediate relief from the sharp, stinging pain caused by peptic ulcers, gastritis, and severe heartburn. This makes it significantly more effective for painful conditions than simple antacid salts alone.

2. Dried Aluminium Hydroxide Gel IP (291 mg): This is a widely trusted antacid agent. It works by chemically neutralizing the excess hydrochloric acid present in the stomach. By raising the pH of the stomach contents, it prevents the acid from eroding the stomach lining and the esophagus. Furthermore, Aluminium Hydroxide has astringent properties and helps form a protective barrier over ulcerated tissue, allowing it to heal without constant acid irritation.

3. Magnesium Hydroxide IP (98 mg): Acting as the second antacid in this formulation, Magnesium Hydroxide is faster-acting than Aluminium salts. It provides quick neutralization of acid. Additionally, Magnesium Hydroxide has a mild laxative effect. This is a crucial formulation detail: Aluminium salts can sometimes cause constipation, while Magnesium salts can cause loose stools. By combining them, Amycaine Suspension balances these side effects, ensuring regular bowel movements while treating acidity.

Therapeutic Indications and Benefits

Amycaine Suspension is indicated for a broad spectrum of gastrointestinal disorders. Its “Anesthetic Antacid” profile makes it particularly useful for:

• Relief from Acidity and Heartburn: It effectively treats the burning sensation in the chest (pyrosis) caused by acid reflux, where stomach acid flows back into the food pipe.

• Treatment of Gastritis: Gastritis involves the inflammation of the stomach lining. The protective coating provided by Amycaine helps reduce this inflammation, soothing the raw, irritated tissues.

• Peptic Ulcer Management: For patients suffering from stomach or duodenal ulcers, the pain can be excruciating, especially on an empty stomach. The Oxetacaine in Amycaine numbs the ulcer site, while the antacids prevent further acid damage, creating an optimal environment for the ulcer to heal.

• Esophagitis: It aids in treating inflammation of the esophagus, often caused by chronic acid reflux (GERD).

• Symptomatic Relief from Bloating: By neutralizing acid, it also aids in relieving the discomfort of indigestion and gas.

Mechanism of Action: The “Protective Shield”

When ingested, Amycaine Suspension coats the mucosal lining of the stomach and esophagus. This physical coating serves two purposes:

1. Protection: It acts as a shield against the corrosive action of pepsin and hydrochloric acid.

2. Neutralization: It instantly begins to raise the gastric pH to a safer level. Simultaneously, the Oxetacaine component binds to the mucosal surface, blocking the depolarization of sensory nerve impulses. This results in a rapid reduction of pain signals sent to the brain, offering the patient relief often within minutes of administration.

Quality Assurance and Packaging

Amista Labs manufactures Amycaine Suspension under strict quality controls. The product carries the WHO-GMP (World Health Organization – Good Manufacturing Practices), GLP (Good Laboratory Practice), and ISO 9001:2015 certifications. These logos, proudly displayed on the packaging, assure patients and doctors of the product’s safety, purity, and efficacy.

The product comes in a 170ml bottle with a palatable Mint Flavour, ensuring patient compliance. Many antacids have a chalky or unpleasant taste, but the mint flavor of Amycaine makes it easier to swallow, leaving a cooling sensation that further aids in feeling relief from heartburn.