Cofzar LS

Cofzar LS Syrup is a potent therapeutic formulation designed to provide comprehensive relief from productive coughs and respiratory congestion. Manufactured by Amista Labs, a pharmaceutical company dedicated to quality and “In Quest of Better Health,” this syrup is a staple in managing respiratory conditions characterized by bronchospasm and thick mucus accumulation.

The product combines three active ingredients—Levosalbutamol, Ambroxol, and Guaiphenesin—to create a synergistic effect that clears airways, loosens phlegm, and eases breathing. It is widely prescribed by General Practitioners (GP), ENT specialists, and Pediatricians for conditions such as bronchitis, asthma, and other pulmonary disorders.

Detailed Composition & Mechanism of Action

Cofzar LS Syrup utilizes a triple-action formula to target different aspects of respiratory distress. Each 5ml of the syrup contains:

1. Levosalbutamol Sulphate IP (1 mg)

• Role: Bronchodilator.

• Function: Levosalbutamol is the active (levo) isomer of salbutamol. It works by stimulating beta-2 adrenergic receptors in the lungs, which relaxes the smooth muscles surrounding the airways.

• Benefit: By relaxing these muscles, the airways dilate (widen), allowing for immediate relief from wheezing, shortness of breath, and chest tightness. Levosalbutamol is preferred over conventional salbutamol because it offers effective bronchodilation with significantly fewer side effects like tremors or heart palpitations.

2. Ambroxol Hydrochloride IP (30 mg)

• Role: Mucolytic Agent.

• Function: Ambroxol works directly on the mucus structure. It breaks down the acid mucopolysaccharide fibers that give sputum its thickness and stickiness.

• Benefit: This action thins the mucus (reduces viscosity), preventing it from adhering to the airway walls. Thinner mucus is much easier for the respiratory system’s cilia to transport upward, allowing the patient to cough it out without excessive strain.

3. Guaiphenesin IP (50 mg)

• Role: Expectorant.

• Function: Guaiphenesin increases the volume and reduces the adhesiveness of respiratory tract secretions. It essentially increases the hydration of the mucus.

• Benefit: By increasing the fluid volume in the airways, it lubricates the irritated respiratory tract and facilitates the removal of slime. It transforms a dry, non-productive cough into a productive one, ensuring the chest is cleared effectively.

Key Therapeutic Indications

Cofzar LS Syrup is indicated for the symptomatic treatment of productive cough associated with bronchospasm in conditions such as:

• Acute and Chronic Bronchitis: Inflammation of the bronchial tubes leading to persistent wet coughs.

• Bronchial Asthma: To relieve airway constriction and help expel mucus triggered by asthmatic episodes.

• COPD (Chronic Obstructive Pulmonary Disease): Helps in managing airflow blockage and breathing-related issues.

• Respiratory Tract Infections: Viral or bacterial infections causing chest congestion and difficulty in expectoration.

Why Choose Cofzar LS?

• Comprehensive Relief: It does not just suppress the cough; it treats the root cause by opening the airways and clearing mucus.

• Patient Comfort: The formulation soothes the throat and reduces the physical exhaustion caused by continuous coughing fits.

• High Quality: Produced in WHO-GMP and GLP certified facilities, ensuring the highest standards of safety and efficacy.

• Economical: Priced at an MRP of 112.50/- per bottle, it offers an affordable solution for effective respiratory care.

Dosage and Administration

• Packing: 100ml Bottle.

• Administration: Oral use only. Shake the bottle well before use to ensure the suspension is mixed evenly.

• Dosage: As directed by the physician.

  • Adults: Typically 10ml, two to three times daily.

  • Children: Dosage should be strictly calculated by a pediatrician based on age and weight.

• Measuring: Always use a measuring cup or spoon for accurate dosing; do not estimate.

Safety Information & Precautions

• Medical Advice: Always consult a doctor before starting this medication, especially for patients with heart conditions, high blood pressure, or diabetes.

• Pregnancy & Lactation: Use only if prescribed by a healthcare professional.

• Side Effects: Common side effects may include mild nausea, vomiting, or tremors. These are usually temporary and subside as the body adjusts to the medication.

• Storage: Store in a cool, dry place, protected from light. Keep out of reach of children.

Cofzar LS Syrup stands as a reliable guardian for respiratory health, ensuring that patients can breathe easy and live comfortably.