Pregabalin IP 75mg + Nortriptyline IP10mg

Comist NT Tablets

Category

Comist NT Tablets by Amista Labs are a prescription-strength combination medicine formulated to manage neuropathic pain and nerve-related disorders effectively. This advanced formulation combines Pregabalin IP 75 mg and Nortriptyline IP 10 mg, two well-established agents that work synergistically to provide enhanced pain relief, improved nerve function, and better quality of life for patients suffering from chronic nerve pain conditions.

Composition

  • Pregabalin IP – 75 mg

  • Nortriptyline IP – 10 mg

Mechanism of Action

Pregabalin acts by binding to specific calcium channels in the nervous system, reducing the release of pain-causing neurotransmitters. This helps calm overactive nerves and decreases abnormal pain signals. Nortriptyline, a tricyclic antidepressant, works by increasing levels of serotonin and norepinephrine in the brain, which play a vital role in pain modulation and mood stabilization. Together, these components provide dual-action pain control, addressing both the physical and psychological aspects of neuropathic pain.

Therapeutic Uses

Comist NT Tablets are widely prescribed for the management of:

  • Diabetic peripheral neuropathy

  • Post-herpetic neuralgia (nerve pain after shingles)

  • Sciatica and radiculopathy

  • Chronic nerve pain due to spinal disorders

  • Neuropathic pain associated with vitamin deficiencies

  • Fibromyalgia and other chronic pain syndromes

This combination is particularly beneficial for patients who do not achieve adequate relief with single-drug therapy.

Benefits of Comist NT Tablets

  • Provides effective relief from burning, tingling, and shooting nerve pain

  • Improves sleep disturbances associated with chronic pain

  • Helps reduce anxiety and depressive symptoms linked to long-term pain

  • Enhances daily functioning and overall quality of life

  • Well-balanced dosage for optimal efficacy with reduced side effects

Dosage and Administration

A physician usually prescribes Comist NT Tablets to be taken once daily, preferably at night to minimize drowsiness. Swallow the tablet whole with water, and do not crush or chew it. The physician may adjust the dosage based on the patient’s condition, age, and response to treatment.

Safety and Precautions

  • Use with caution in patients with kidney impairment, heart conditions, or a history of depression

  • Avoid alcohol consumption as it may enhance drowsiness and dizziness

  • Not recommended during pregnancy or breastfeeding unless advised by a doctor

  • Patients should avoid driving or operating heavy machinery until they know how the medicine affects them

Possible Side Effects

Comist NT Tablets may cause side effects such as dizziness, drowsiness, dry mouth, constipation, weight gain, or blurred vision. These effects usually remain mild and temporary. Patients should report any persistent or severe symptoms to a healthcare professional immediately.

Additional information

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