Coxita-120

Coxita-120 Tablets by Amista Labs are a powerful and effective medication formulated to provide fast and long-lasting relief from pain and inflammation associated with various musculoskeletal and inflammatory conditions. Each tablet contains Etoricoxib 120 mg, a selective COX-2 inhibitor known for its strong analgesic and anti-inflammatory properties with a comparatively lower risk of gastric side effects.

Composition

Each film-coated tablet contains:
Etoricoxib IP – 120 mg
Excipients – q.s.

Mechanism of Action

To understand the efficacy of Coxita-120 Tablets, it is essential to look at its active ingredient, Etoricoxib. The body produces enzymes known as Cyclooxygenase (COX). There are two main types: COX-1 (which protects the stomach lining) and COX-2 (which produces prostaglandins that cause pain and inflammation).

Traditional NSAIDs inhibit both enzymes, leading to pain relief but also stomach ulcers or irritation. Coxita-120 Tablets is a highly selective COX-2 inhibitor. It specifically targets the enzyme responsible for pain and inflammation while sparing the enzyme responsible for protecting the stomach. This selectivity allows Coxita-120 Tablets to deliver powerful anti-inflammatory and analgesic effects with a significantly reduced risk of gastrointestinal complications compared to older NSAIDs.

Key Indications and Uses

The 120mg strength of Etoricoxib found in Coxita-120 Tablets is typically the highest dosage prescribed and is generally reserved for acute phases of pain or severe chronic conditions. It is indicated for:

1. Acute Gouty Arthritis: Gout is characterized by sudden, severe attacks of pain, swelling, redness, and tenderness in one or more joints. Coxita-120 Tablets is highly effective in rapidly reducing this intense inflammation and pain during flare-ups.

2. Rheumatoid Arthritis (RA): A chronic inflammatory disorder affecting joint linings. Coxita-120 Tablets helps manage the swelling and stiffness, allowing patients better mobility.

3. Ankylosing Spondylitis: An inflammatory disease that, over time, can cause some of the small bones in the spine to fuse. This product helps alleviate the chronic pain and stiffness associated with this condition.

4. Post-Operative Dental Pain: Due to its strong analgesic properties, the 120mg dosage is often used for short-term treatment of moderate to severe pain following dental surgery.

5. Osteoarthritis: While lower doses are often used for maintenance, Coxita-120 Tablets may be used for symptom relief during severe episodes of joint pain.

Dosage and Administration

Coxita-120 Tablets is typically designed for oral administration. Due to the high potency of the 120mg dosage, it is often prescribed as a once-daily medication. For conditions like acute gout, the course is usually short-term (e.g., restricted to a maximum of 8 days) to manage the acute flare, after which the dosage might be reduced. The tablet can usually be taken with or without food, though taking it at the same time every day helps maintain consistent blood levels of the medication.

Amista Labs: A Commitment to Quality

Amista Labs positions Coxita-120 Tablets as a flagship product in its pain management portfolio. The manufacturing process adheres to rigorous industrial standards to ensure purity, stability, and efficacy. The packaging—visible as a professional 10×10 blister pack—ensures the medication is protected from moisture and contamination, maintaining its integrity until consumption. By choosing Amista Labs, patients and prescribers are opting for a product backed by a dedication to healthcare innovation and safety.

Safety and Precautions

While Coxita-120 Tablets offers a superior gastrointestinal safety profile compared to non-selective NSAIDs, it is a potent medication that requires responsible use.

• Cardiovascular Health: As with all COX-2 inhibitors, long-term use at high dosages may increase the risk of cardiovascular events. It is used with caution in patients with high blood pressure or heart history.

• Contraindications: It is generally not recommended for patients with active peptic ulcers, severe heart failure, or uncontrolled hypertension.

• Pregnancy and Lactation: Consultation with a doctor is strictly required before use during pregnancy or breastfeeding.