Coxita-Plus

Coxita-Plus is a premium pharmaceutical formulation brought to you by Amista Labs, a company renowned for its commitment to quality healthcare (“In Quest of Better Health”). This product represents a powerful synergy between two distinct classes of pain-relieving medications, designed specifically to combat moderate to severe pain, inflammation, and stiffness associated with various orthopedic conditions.

By combining the targeted anti-inflammatory properties of Etoricoxib with the trusted analgesic benefits of Paracetamol, Coxita-Plus offers a comprehensive solution for patients seeking rapid and sustained relief from musculoskeletal disorders.

Composition Analysis

The efficacy of Coxita-Plus lies in its scientifically balanced formulation:

1. Etoricoxib IP (60mg): Etoricoxib belongs to a class of drugs known as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), specifically the subclass of selective COX-2 inhibitors. Unlike traditional NSAIDs that inhibit both COX-1 (protective of the stomach lining) and COX-2 (responsible for pain and inflammation) enzymes, Etoricoxib selectively targets only the COX-2 enzyme.

• Role: It effectively blocks the production of prostaglandins, the chemical messengers that cause pain and swelling at the site of injury or disease.

• Advantage: Because it spares the COX-1 enzyme, it generally offers a better safety profile regarding gastrointestinal side effects compared to older painkillers like Diclofenac or Ibuprofen.

2. Paracetamol IP (325mg): Paracetamol (Acetaminophen) is a widely used analgesic (pain reliever) and antipyretic (fever reducer).

• Role: It works centrally in the brain to increase the pain threshold, making the body feel pain less intensely.

• Synergy: When combined with Etoricoxib, Paracetamol enhances the overall pain-relieving effect, providing a dual-action mechanism that attacks pain from both the peripheral nervous system (at the injury site) and the central nervous system.

Key Therapeutic Uses

Coxita-Plus is indicated for the symptomatic relief of pain and inflammation in a variety of conditions. As highlighted in the product specifications, it is primarily effective for:

• Osteoarthritis & Rheumatoid Arthritis: It significantly reduces the joint stiffness, swelling, and chronic pain associated with degenerative joint diseases, helping patients regain movement.

• Ankylosing Spondylitis: Helpful in managing the inflammation of the spine and large joints.

• Acute Gouty Arthritis: Provides relief during painful gout flare-ups.

• Musculoskeletal Injuries: Ideal for treating sprains, strains, lower back pain, and sports injuries where inflammation is a key component.

• Post-Operative Pain: often prescribed following dental or minor orthopedic surgeries to manage recovery pain.

Benefits of Coxita-Plus

• Dual Action: Relieves pain while simultaneously reducing inflammation.

• Improved Mobility: By reducing stiffness in joints and muscles, it supports better physical mobility for patients restricted by arthritis.

• Rapid Onset: The formulation is designed for quick absorption to provide fast relief.

• Patient Compliance: The combination of two drugs in a single tablet reduces the pill burden on patients who would otherwise need to take separate medications.

Quality & Packaging

Amista Labs ensures that Coxita-Plus meets the highest standards of safety and efficacy.

• Certifications: The product is manufactured in facilities that adhere to WHO-GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practice) standards. The company is also ISO 9001:2015 certified.

• Premium Packing: Coxita-Plus comes in Alu-Alu packaging. This creates a barrier against oxygen, moisture, and light, ensuring the tablets remain stable and effective throughout their shelf life. The box contains 10 strips of 10 tablets each (10×10), making it a convenient stock size for pharmacies.

Dosage and Safety Information

• Dosage: As directed by a registered medical practitioner. It is generally recommended to take the tablet whole with water, preferably after meals to avoid potential gastric upset.

• Precautions: Patients with a history of liver disease, kidney issues, or severe heart conditions should consult their doctor before using this medication. Avoid alcohol consumption while on this medication as it may increase the risk of liver damage due to Paracetamol.