Rabeprazole 20mg + Domperidone 10mg

Reebo D Tablet is an advanced gastro-intestinal formulation developed by Amista Labs, designed to provide effective relief from acid-related stomach disorders and motility-related digestive issues. This combination medicine contains Rabeprazole 20mg and Domperidone 10mg, working synergistically to reduce gastric acid secretion while improving gastrointestinal motility. Reebo D Tablet is widely prescribed for the management of gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, and peptic ulcer disease.

Composition and Strength

Reebo D Tablet is a fixed-dose combination medication. Each tablet contains:

• Rabeprazole Sodium: 20mg

• Domperidone: 10mg

This dual-action formula makes it a “Gastro” category staple, widely prescribed by general practitioners and gastroenterologists for its synergistic effect in treating upper gastrointestinal tract issues.

Mechanism of Action: How Reebo D Works

To understand the efficacy of Reebo D, it is essential to look at how its two active ingredients function together:

1. Rabeprazole (20mg): Rabeprazole belongs to a class of medications known as Proton Pump Inhibitors (PPIs). It works by blocking the enzyme in the stomach wall responsible for producing acid (the proton pump). By reducing the amount of acid produced, Rabeprazole prevents damage to the stomach lining and esophagus, allowing ulcers to heal and preventing heartburn. It is known for its fast onset of action compared to other PPIs.

2. Domperidone (10mg): Domperidone is a prokinetic agent. It works on the upper digestive tract to increase the movement of the stomach and intestines. This action facilitates faster gastric emptying, ensuring that food moves through the digestive system more efficiently. Additionally, Domperidone acts as an anti-emetic, helping to prevent sensations of nausea and vomiting often associated with severe acidity.

Key Therapeutic Indications

According to the usage guidelines provided, Reebo D is indicated for a variety of conditions:

• Acid-Related Stomach Disorders (GERD): This is the primary use case. When stomach acid flows back into the tube connecting your mouth and stomach (esophagus), it causes irritation. Reebo D reduces the acid and prevents this backflow.

• Dyspepsia: Commonly known as indigestion, this condition is characterized by upper abdominal pain, bloating, and nausea. The combination of acid suppression and improved motility relieves these symptoms effectively.

• Gastroparesis: This is a condition that affects the stomach muscles and prevents proper stomach emptying. The Domperidone in Reebo D is specifically effective here, helping to “kickstart” the digestive process.

• Peptic Ulcers: These are sores that develop on the lining of the stomach, small intestine, or esophagus. By reducing the acidity of the stomach environment, Reebo D creates favorable conditions for these ulcers to heal.

• Helicobacter pylori Infection: Often used as part of a triple therapy (alongside antibiotics) to treat H. pylori bacterial infections which are a common cause of ulcers.

Packaging and Quality Assurance

Amista Labs places a strong emphasis on product stability and shelf life.

• Packing: Reebo D comes in 10×10 Alu-Alu packaging. “Alu-Alu” (Aluminum-Aluminum) blister packs offer the highest level of protection against moisture, oxygen, and light. This is critical for Rabeprazole, which can be sensitive to moisture, ensuring the tablet remains effective until the moment it is consumed.

• Certifications: The product is manufactured under strict GLP (Good Laboratory Practice) and WHO-GMP guidelines, ensuring consistent quality in every batch.

Dosage and Administration

• Recommended Dosage: Typically, doctors prescribe one tablet daily, preferably taken in the morning on an empty stomach (at least 30 minutes before breakfast). This timing allows the Rabeprazole to inhibit the acid pumps effectively when they are most active.

• Precautions: Patients should consult a healthcare provider before use, especially those with pre-existing liver or kidney conditions, or cardiac issues.