Furex-500 Tablets

Furex-500 Tablets by Amista Labs are a high-quality antibiotic formulation containing Cefuroxime IP 500 mg, a second-generation cephalosporin antibiotic widely prescribed for the treatment of various bacterial infections. Manufactured under stringent quality standards, Furex-500 Tablets offers reliable efficacy, safety, and patient compliance, making it a trusted choice among healthcare professionals.

Composition and Active Ingredient

Each uncoated tablet of Furex-500 Tablets contains:

• Cefuroxime Axetil I.P.: Equivalent to Cefuroxime 500 mg.

Cefuroxime is a second-generation cephalosporin antibiotic. The “Axetil” portion of the molecule is an ester prodrug form, which allows the medication to be absorbed effectively through the gastrointestinal tract. Once absorbed, it is hydrolyzed into active cefuroxime in the bloodstream, ready to target infection sites. The designation “I.P.” stands for Indian Pharmacopoeia, ensuring the product meets the rigorous quality standards set by Indian pharmaceutical regulations.

Mechanism of Action: How Furex-500 Tablets Works

Furex-500 Tablets is a bactericidal agent, meaning it kills bacteria rather than just inhibiting their growth. It achieves this by interfering with the synthesis of the bacterial cell wall.

Bacteria require a rigid cell wall to survive and protect themselves from their environment. Cefuroxime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final stage of peptidoglycan synthesis—essentially blocking the construction of the cell wall. Without this structural support, the bacterial cell becomes unstable and bursts (lyses), leading to the eradication of the infection.

Key Indications and Uses

Due to its broad spectrum of activity, Furex-500 Tablets is indicated for the treatment of mild to moderate infections caused by susceptible organisms. Common uses include:

1. Respiratory Tract Infections: It is highly effective against lower respiratory tract infections such as pneumonia, acute bronchitis, and acute exacerbations of chronic bronchitis.

2. ENT (Ear, Nose, and Throat) Infections: Doctors frequently prescribe Furex-500 Tablets for otitis media (middle ear infection), sinusitis (sinus infection), tonsillitis, and pharyngitis.

3. Skin and Soft Tissue Infections: It treats conditions such as cellulitis, furunculosis (boils), and impetigo caused by Staphylococcus aureus or Streptococcus pyogenes.

4. Urinary Tract Infections (UTIs): It is used for uncomplicated urinary tract infections, such as cystitis and pyelonephritis.

5. Lyme Disease: It is one of the few oral antibiotics effective for treating early-stage Lyme disease (erythema migrans).

Dosage and Administration

• Standard Dosage: The typical adult dose for most infections is 250 mg to 500 mg twice daily. Furex-500 Tablets represents the higher strength, often used for more severe infections (like pneumonia or Lyme disease).

• Take with Food: Cefuroxime Axetil has better bioavailability when taken with food. Taking the tablet after a meal not only helps the body absorb the medicine more efficiently but also reduces the chance of stomach upset.

• Swallow Whole: The tablet should be swallowed whole with water. Crushing or chewing the tablet is generally advised against because Cefuroxime Axetil has a very bitter taste.

Side Effects and Safety Profile

Furex-500 Tablets is generally well-tolerated, but like all medications, it may cause side effects in some individuals. Common side effects are usually mild and transient:

• Nausea and vomiting

• Diarrhea

• Abdominal pain

• Headache or dizziness

Allergic Reactions: Patients with a known allergy to cephalosporins or penicillins should exercise caution. Although cross-sensitivity with penicillin is low, it is crucial to inform the doctor of any past allergic reactions to antibiotics.

Packaging and Storage

As seen in the image, Furex-500 Tablets by Amista comes in a secure box packaging, typically containing a blister strip (indicated by “5×6 Tablets” on the box, suggesting a pack of 30 tablets total or strips of 6). The packaging protects the tablets from moisture and light.

• Storage: Store in a cool, dry place protected from light. Keep out of reach of children.