Placin TH 4

Placin TH 4 Tablet is a specialized pharmaceutical product marketed by Amista Labs, a company operating under the slogan “In Quest of Better Health.” Categorized under “Ortho” (Orthopedics), this medication is a fixed-dose combination drug designed to manage painful musculoskeletal conditions.

The product is formulated to address the dual challenges of inflammation and muscle stiffness, effectively breaking the pain-spasm cycle that often accompanies orthopedic injuries and chronic joint disorders.

Composition and Strength

The efficacy of Placin TH 4 lies in its synergistic composition. Each tablet contains two active pharmaceutical ingredients (APIs):

• Aceclofenac (IP) 100 mg: Aceclofenac belongs to a class of drugs known as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). It is widely recognized for its analgesic (pain-relieving) and anti-inflammatory properties. It works by blocking the action of cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins—chemical messengers that cause pain and inflammation at the site of injury or damage.

• Thiocolchicoside (IP) 4 mg: Thiocolchicoside is a semi-synthetic muscle relaxant derived from the colchicum flower. It acts on the central nervous system to relieve muscle stiffness and spasms. Unlike some older muscle relaxants, Thiocolchicoside is generally known for having a lower sedative profile, allowing for muscle relaxation without inducing heavy drowsiness.

Therapeutic Indications and Usage

According to the promotional material, Placin TH 4 is indicated for a variety of conditions affecting the muscles and joints. The manufacturer highlights the following key benefits:

• Relief from Muscle Spasms: It effectively targets and relaxes rigid muscles, relieving the tightness that often limits movement.

• Pain and Inflammation Reduction: The Aceclofenac component works to bring down swelling and acute pain.

• Management of Spinal Issues: It is particularly noted for managing back pain and neck pain, which are often caused by conditions like spondylitis or mechanical strain.

• Joint Disorders: The formulation helps in managing pain associated with joint disorders where muscle tightening is a secondary symptom.

• Post-Injury Recovery: It supports faster recovery in musculoskeletal injuries (such as sprains and strains) by enhancing mobility.

• Quality of Life: By restoring mobility and reducing pain, the medication aims to improve the overall quality of daily life for the patient.

Mechanism of Action: The Synergistic Effect

In many orthopedic conditions, pain and muscle spasms create a vicious cycle. Pain causes the muscles to contract defensively (spasm) to immobilize the area, but the spasm itself causes further pain.

Placin TH 4 addresses both sides of this equation simultaneously. The Aceclofenac reduces the chemical signals of pain, while the Thiocolchicoside physically relaxes the muscle fibers. This combination is generally considered more effective than using a painkiller alone for conditions involving muscle tightness.

Quality and Manufacturing Standards

The packaging and promotional material emphasize high manufacturing standards. Amista Labs highlights several key certifications:

• WHO GMP Certified: Indicates the product is manufactured according to World Health Organization Good Manufacturing Practices, ensuring consistent quality.

• GLP (Good Laboratory Practice): Ensures that the laboratory studies and testing were conducted effectively.

• ISO 9001:2015: A standard that demonstrates the organization’s ability to consistently provide products that meet customer and regulatory requirements.

Packaging and Pricing

• Packaging: The product comes in an Alu-Alu blister pack. This is a premium packaging type where aluminum foil is used on both the top and bottom. This provides superior protection against oxygen, moisture, and light, ensuring the stability of the Aceclofenac and Thiocolchicoside until the moment of consumption.

• Pack Size: A standard box contains 10 strips of 10 tablets (10×10).

• MRP: The Maximum Retail Price listed is ₹1828.13/- per Box.

Important Medical Disclaimer

The image clearly shows the Rx symbol on the box, indicating that Placin TH 4 is a prescription-only medicine.

• Consultation Required: This medication should only be taken under the guidance of a qualified medical practitioner.

• Contraindications: NSAIDs like Aceclofenac may not be suitable for individuals with a history of stomach ulcers, kidney issues, or heart conditions.

• Usage: Patients should strictly adhere to the dosage prescribed by their doctor to avoid potential side effects such as gastric irritation or nausea.